Visible-light-activated copper(I) catalyzed oxidative Csp–Csp cross-coupling reaction: efficient synthesis of unsymmetrical conjugated diynes without ligands and base

 

A novel visible-light-promoted copper-catalysed process for the Csp–Csp cross-coupling reaction of terminal alkynes at room temperature is described. The current photochemical method is simple, highly functional group compatible, and more viable towards the construction of bio-active 1,3-unsymmetrical conjugated diynes without the need of bases/ligands, additives and expensive palladium/gold catalysts.

Visible-light-activated copper(I) catalyzed oxidative Csp-Csp cross-coupling reaction: efficient synthesis of unsymmetrical conjugated diynes without ligands and base

Green Chem., 2016, Advance Article
DOI: 10.1039/C6GC01463A, Communication
Arunachalam Sagadevan, Ping-Chiang Lyu, Kuo Chu Hwang
An efficient and eco-friendly approach to Csp-Csp cross-coupling of terminal alkynes for the construction of unsymmetrical conjugated diynes via a visible-light-induced CuCl catalysed process at room temperature is described.
Communication

Visible-light-activated copper(I) catalyzed oxidative Csp–Csp cross-coupling reaction: efficient synthesis of unsymmetrical conjugated diynes without ligands and base

*Corresponding authors
aDepartment of Chemistry, National Tsing Hua University, Hsinchu, Republic of China
bInstitute of Bioinformatics and Structural Biology and College of Life Sciences, National Tsing Hua University, Hsinchu, Republic of China
E-mail: kchwang@mx.nthu.edu.tw
Fax: +886 35711082
Green Chem., 2016, Advance Article

http://pubs.rsc.org/en/Content/ArticleLanding/2016/GC/C6GC01463A?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+rss%2FGC+%28RSC+-+Green+Chem.+latest+articles%29#!divAbstract
DOI: 10.1039/C6GC01463A

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////////Visible-light-activated,  copper(I) catalyzed,  oxidative Csp–Csp cross-coupling reaction,  unsymmetrical conjugated diynes