Greener, cheaper, safer drugs and perfume using iron

photo of perfume bottles on a tray

Researchers say iron can replace the rare and sometimes toxic compounds used to create perfumes and drugs (photo by Jenn Durfey via Flickr)

University of Toronto researchers have developed safer, cheaper and more environmentally-friendly techniques to produce compounds commonly used in drugs and perfumes.

Researchers used the  new techniques to create active, iron-based catalysts. These catalysts are needed to produce certain compounds used in the drug and perfume industries.  read all here

Eco-Catalysis Leads the Way to Green Synthetic Chemistry

EcoCatalysis Leads the Way to Green Synthetic Chemistry

by H Jianwei – ‎2012

Sep 25, 2012 – Research Article. Open Access. Volume 1 • Issue 4 • 1000e114. Organic Chem Curr Res. ISSN:2161-0401 OCCR an open access journal.

A new method for synthesising model lignin oligomers will help scientists turn plant matter into biofuel

Lignin is a complex and random polymer. This representative substructure shows some of the common linkages in lignin

A new method for synthesising model lignin oligomers will help scientists turn plant matter into biofuel

Unlike cellulose, a plant cell wall component with a repeating polymer structure, lignin is a complex and random polymer. The chemical units are linked by different connectivities, so one single process cannot attack all of these bonds. Previously, monomers and dimers were used to model chemical linkages of lignin, but were too simple for the study of lignin itself. More complex trimers, tetramers and hexamers have been synthesised, but with inefficient, low-yielding methods.  read all at

New software for creating green solvents

The GRASS software has a green chemistry-focussed approach to solvent design

Scientists in France have developed a computer-assisted organic synthesis program to design sustainable solvents from bio-based building blocks.


Finding clean, sustainable alternatives to petroleum-derived solvents and chemicals is a matter of increasing urgency in the chemical industry worldwide.

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Atheroprotective Activity of Spirulina

Atheroprotective activity of Spirulina may be due to it having a protein with a similar structure to bilirubin

Spirulina platensis, a water blue-green alga and food supplement due to its high amount of proteins, polysaccharides, and vitamins, has been associated with potent biological effects.

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Atheroprotective Activity of Spirulina

In order for our body to ensure all organ functions it needs natural nutrients in the best and highest concentration. Spirulina’s “natural treasure chest” contains a unique and balanced combination of the highest levels of natural substances that are essential for good health. Spirulina has a very thin cell wall, which enables vital nutrients to be easily absorbed by the body.

Spirulina in comparison

Spirulina contains more than 4.000 vital substances and nutrients and it is also nutritionally superior compared to usual foods.

Spirulina contains:

  • 300 % more calcium than unskimmed milk
  • 2.300 % more iron than spinach
  • 3.900 % more beta-carotene than carrots
  • 375 % more protein than tofu

Further information:

Crystal Structure of C-Phycocyanin from Spirulina Platensis.
Crystal structure of Spirulina platensis for Phycocyanin with PDB ID 1GH0 was revealed to contain 24 chains named from 1GH0A to 1GH0X. It was observed that the alternate chains consisted of same sequence however, the odd chains (1GH0A, 1GH0C, 1GH0E… 1GH0W) and even chains (1GH0B, 1GH0D, 1GH0F… 1GH0X) contained 162 and 172 amino acid residues respectively in a similar pattern. Sequence comparison revealed 100 BLAST hits and phylogenetic tree was traced for alternate chains. Similarity percentages of hits were calculated for 1GH0A chain was revealed to have 84 % hits of cyanobacterial sequences, 12 % hits of rhodophyta sequences, and 4% hits of eugliphida, cyanophora and artificial vector sequences respectively. Similarity percentages of hits were calculated for 1GH0B chain was revealed to have 73 % hits of cyanobacterial sequences, 20% hits of rhodophyta sequences, and 5% hits of cryptophyta
sequences, and 1% hits of eugliphida and 1% hits of cyanophora sequences respectively. Structure comparisons of these sequences examined by VAST showed residues of alternate entire chains from 1 to 162 and from 1 to 172 residues to contain 1323 structure neighbors. 1628 structure neighbors were found for the phycobilisome domain family which is the major accessory lightharvesting complexes of cyanobacteria and red algae.
Sequence and Structure Comparison Studies of Phycocyanin in Spirulina Platensis
Lakshmi P.T.V.1 *, Uma Maheswari S.1, Karthikeyan P.P.1, Annamalai A.2
1Phytomatics Laboratory, Department of Bioinformatics, Bharathiar University, Coimbatore- 46, Tamil Nadu, India,
Fax. 0422-2424387; E-mail:,
1Department of Bioinformatics, Aloysius Institute of Computer Sciences, St. Aloysius   College, Light House Hill,
Mangalore -3, Karnataka, India. E. mail:
2Plant Cell and Molecular Biology Laboratory, School of Biotechnology, Karunya University,  Coimbatore – 114.  Tamil   Nadu, India,  E. mail:
*Corresponding author: Dr. Lakshmi, P.T.V.,
Email  :

Cocultures of microalgae and cyanobacteria show higher biomass production for biofuel than their monocultures

Working Together


Cocultures of microalgae and cyanobacteria show higher biomass production for biofuel than their monocultures

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Organocatalytic 1,3-dipolar cycloaddition reactions of ketones and azides with water as a solvent


Green Chem., 2013, 15,2384-2388
DOI: 10.1039/C3GC41126E, Communication
Corresponding authors
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore
E-mail: ;
Fax: (+)65-6516-1691
HuBei Collaborative Innovation Center of Non-power Nuclear Technology, Hubei University of Science and Technology, Hubei Province, China

Received 12 Jun 2013, Accepted 19 Jul 2013
First published online 22 Jul 2013

We reported an enamine catalyzed strategy to fully promote a 1,3-dipolar cycloaddition to access a vast pool of substituted 1,2,3-triazoles in water.