Cross-Coupling Triple Play Green Chemistry: Popular reactions using specialized boron reagents can now be run in water

THREE-IN-ONE STRATEGY
In aqueous micelle solutions made using the surfactant TPGS-750-M, even unstable 2-pyridyl boronates readily undergo Suzuki-Miyaura cross-coupling.
Chemists have taken one of the most widely used reactions in organic synthesis—the Suzuki-Miyaura cross-coupling reaction—and made it even more versatile by melding it with an award-winning green chemistry technology. The new development will help researchers, particularly those working in drug discovery, expand the range of compounds that can be made using the cross-coupling approach and create safer and environmentally friendly processes that avoid organic solvents, excess reagents, and high temperatures.

CHINESE MEDICINE-Xuezhikang , A blood lipid regulator

New Drug Approvals

Xuezhikang

Xuezhikang, the extract of red yeast rice, has been widely used as a Chinese traditional medicine for the therapy of patients with cardiovascular diseases. It contains natural Lovastatin and its homologues, as well as unsaturated fatty acids, flavonoids, plant sterols and other biologically active substances

The product is a world-recognized blood lipid regulator, which is made by extracting from “specially-made red yeast rice”. It combines modern high-tech biotechnology with traditional Chinese medicine, which can safely and effectively regulate blood lipids in a comprehensive way with proven curative effects and reliable safety.

Pharmacological Effects: the product can reduce blood cholesterol, triglycerides, low density lipoprotein cholesterol, improve high density lipoprotein cholesterol, inhibit atherosclerotic plaque formation, and protect vascular endothelial cells; and inhibit lipid deposition in the liver. The large-scale evidence-based research has proven that long-term use of XUEZHIKANG can greatly reduce the risk of CHD occurrence and decrease the mortality. XUEZHIKANG…

View original post 1,657 more words