Systematic name
Other names
1,3-dioxolane, 2-[2,5-bis(3,3-dimethyl-1-butyn-1-yl)-4-[2-(3,5-di-1-pentyn-1-ylphenyl)ethynyl]phenyl]
618904-86-2  cas

NanoPutians are a series of organic molecules whose structural formulae resemble human forms.[1] James Tour et al. (Rice University) designed and synthesized these compounds in 2003 as a part of a sequence of chemical education for young students.[2] The compounds consist of two benzene rings connected via a few carbon atoms as the body, four acetylene units each carrying an alkyl group at their ends which represents the hands and legs, and a 1,3-dioxolane ring as the head. Tour and his team at Rice University used the NanoPutians in their NanoKids educational outreach program. The goal of this program was to educate children in the sciences in an effective and enjoyable manner. They have made several videos featuring the NanoPutians as anthropomorphic animated characters.
Construction of the structures depends on Sonogashira coupling and…

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Atheroprotective Activity of Spirulina

Atheroprotective activity of Spirulina may be due to it having a protein with a similar structure to bilirubin

Spirulina platensis, a water blue-green alga and food supplement due to its high amount of proteins, polysaccharides, and vitamins, has been associated with potent biological effects.

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Atheroprotective Activity of Spirulina

In order for our body to ensure all organ functions it needs natural nutrients in the best and highest concentration. Spirulina’s “natural treasure chest” contains a unique and balanced combination of the highest levels of natural substances that are essential for good health. Spirulina has a very thin cell wall, which enables vital nutrients to be easily absorbed by the body.

Spirulina in comparison

Spirulina contains more than 4.000 vital substances and nutrients and it is also nutritionally superior compared to usual foods.

Spirulina contains:

  • 300 % more calcium than unskimmed milk
  • 2.300 % more iron than spinach
  • 3.900 % more beta-carotene than carrots
  • 375 % more protein than tofu

Further information:

Crystal Structure of C-Phycocyanin from Spirulina Platensis.
Crystal structure of Spirulina platensis for Phycocyanin with PDB ID 1GH0 was revealed to contain 24 chains named from 1GH0A to 1GH0X. It was observed that the alternate chains consisted of same sequence however, the odd chains (1GH0A, 1GH0C, 1GH0E… 1GH0W) and even chains (1GH0B, 1GH0D, 1GH0F… 1GH0X) contained 162 and 172 amino acid residues respectively in a similar pattern. Sequence comparison revealed 100 BLAST hits and phylogenetic tree was traced for alternate chains. Similarity percentages of hits were calculated for 1GH0A chain was revealed to have 84 % hits of cyanobacterial sequences, 12 % hits of rhodophyta sequences, and 4% hits of eugliphida, cyanophora and artificial vector sequences respectively. Similarity percentages of hits were calculated for 1GH0B chain was revealed to have 73 % hits of cyanobacterial sequences, 20% hits of rhodophyta sequences, and 5% hits of cryptophyta
sequences, and 1% hits of eugliphida and 1% hits of cyanophora sequences respectively. Structure comparisons of these sequences examined by VAST showed residues of alternate entire chains from 1 to 162 and from 1 to 172 residues to contain 1323 structure neighbors. 1628 structure neighbors were found for the phycobilisome domain family which is the major accessory lightharvesting complexes of cyanobacteria and red algae.
Sequence and Structure Comparison Studies of Phycocyanin in Spirulina Platensis
Lakshmi P.T.V.1 *, Uma Maheswari S.1, Karthikeyan P.P.1, Annamalai A.2
1Phytomatics Laboratory, Department of Bioinformatics, Bharathiar University, Coimbatore- 46, Tamil Nadu, India,
Fax. 0422-2424387; E-mail:,
1Department of Bioinformatics, Aloysius Institute of Computer Sciences, St. Aloysius   College, Light House Hill,
Mangalore -3, Karnataka, India. E. mail:
2Plant Cell and Molecular Biology Laboratory, School of Biotechnology, Karunya University,  Coimbatore – 114.  Tamil   Nadu, India,  E. mail:
*Corresponding author: Dr. Lakshmi, P.T.V.,
Email  :

Greening the Valsartan Synthesis: Scale-up of Key Suzuki–Miyaura Coupling over SiliaCat DPP-Pd

New Drug Approvals



CAS 137862-53-4

Molecular FormulaC24H29N5O3, Average mass435.519 Da

(2S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoic acid


Greening the Valsartan Synthesis: Scale-up of Key Suzuki–Miyaura Coupling over SiliaCat DPP-Pd

 SiliCycle Inc., 2500 Parc-Technologique Blvd, Quebec City, Quebec, Canada G1P 4S6
 Istituto per lo Studio dei Materiali Nanostrutturati, CNR, via U. La Malfa 153, 90146 Palermo, Italy
Org. Process Res. Dev., Article ASAP
DOI: 10.1021/op400118f
Publication Date (Web): June 17, 2013
Abstract Image

The study of the scale-up of the heterogeneous Suzuki-Miyaura coupling reaction in batch conditions between 2-chlorobenzonitrile and 4-tolylboronic acid, a key step in valsartansynthesis, to produce 4′-methyl-2-biphenylcarbonitrile over the SiliaCat DPP-Pd catalyst in ethanol under reflux allows to identify the optimal reaction conditions.

The catalyst, regardless of limited…

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Special Solvent Theme Issue of Green Chemistry

Green Chemistry @ MUN

Walter Leitner (Chair of the Green Chemistry Editorial Board) has written a piece in their blog

It is about a special online theme issue of the journal based on presentations at the 2012 Green Solvents conference organized by Dechema in Boppard, Germany last October.

Fran’s perspective is one of the articles included.

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Cocultures of microalgae and cyanobacteria show higher biomass production for biofuel than their monocultures

Working Together


Cocultures of microalgae and cyanobacteria show higher biomass production for biofuel than their monocultures

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GLENMARK- ELOVERA , for dry skin disorders

New Drug Approvals

Elovera extract 10% cream, Vitamin E 0.5%

Category–Locally Acting Skin Preparations


* Aqueeze adequate amount of elovera moisturizing body wash onto wet hands or wet loran and work into a creamy lather. apply it all ovr the body, keep for some time and then rinse with water.

Products Name :Elovera Moisturizing Body Wash 150ml – (Glenmark)


Elovera Cream, manufacture by Glenmark pharmaceuticals limited , is cream enriched with vitamin E and Aloe Vera. It’s a very special cream specially for treating scars and other minor pimple spots on the face.

reviews from net

My skin is very much oily hence I get these ugly Pimples very profoundly. On top of it i have the habit of bursting out the puss from these pimples. I always play it with my hands and as a result forms some very ugly scars on my face which are visible…

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